NFL Betting Lines – Colts at Bills Matchup

NFL betting lines for the Indianapolis Colts at Buffalo Bills matchup will be based on the complicated NFL odds formula of a number one seed for the playoffs having no reason to risk starters to injury going against a last place team with nothing to lose.

Indianapolis is a formidable team with the NFL betting lines when they are playing their starters but as was demonstrated last week with the NFL odds they are not at all imposing when they rest their key players. The Colts are coming off their first straight up loss of the season with the NFL betting lines in a 15-29 sports betting decision against the New York Jets.

The Colts have one of the top ranked offenses with the NFL betting lines this year as they rank 6th in scoring and 7th best with the NFL lines for points allowed.

The Buffalo Bills, conversely, rank as one of the worst offensive teams with the NFL betting lines this year as they are 29th in scoring. The defense has been slightly more effective with the NFL betting lines as it ranks 20th in points allowed.

Bills quarterback Ryan Fitzpatrick is listed as questionable for this matchup against the Colts with the NFL betting lines. Brian Brohm started in his place last week and was ineffective in a 3-31 loss with the NFL betting lines at Atlanta. No matter who starts for the Bills they are likely going to want to get the game over with just as badly as the Colts. This makes for a challenging handicap.

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